Researchers in Europe say a new type of biological molecule called nanobodies, or miniantibodies, can block inflammation and reduce pain in mice — a technique they describe as a next-generation strategy against inflammatory diseases.
In experiments on mice, the nanobodies appeared to be more effective at controlling inflammation than either regular antibodies or the anti-inflammatory drugs that are typically used, the researchers said. The nanobodies could one day be a potent treatment for chronic pain, inflammatory bowel disease, multiple sclerosis and other inflammatory disorders, they said.
The research team also tested these nanobodies in a sample of human blood. The team members found that the nanobodies were 1,000 times more potent in hindering the release of inflammatory molecules than similar, small-molecule drug candidates. [The 7 Biggest Mysteries of the Human Body]